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Product ID: 227830

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LUMAKRAS is a medicine widely used to treat adults with non-small cell lung cancer (NSCLC) that has enhanced to other parts of the body or is resistant to surgery. Its tumor has an aberrant KRAS G12C gene, and those who have had at least one prior treatment for their cancer.

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120mg*240 Tablets
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Lumakras is a medication that can be taken orally and is used to treat a specific type of lung cancer. This cancer occurs in the alveoli. Non-small cell lung cancer also referred to as NSCLC, is the term of the disease. When the tumor has spread to other areas of the body or when it is resistant to the surgical procedures that are being used to treat it, the doctor will typically prescribe this medicine. 

And whose tumor is positive for KRAS, as well as those who have already undergone at least one treatment in the past. Lumakras is only approved for the treatment of locally advanced or metastatic non-small cell lung tumors at this time. This is the indication for which the evidence from clinical trials conducted by Amgen is most supportive of the drug's effectiveness.

Things to keep in mind before using it

You are only allowed to take this medication as directed by your physician, and only when they have prescribed it to you. Taking this medication without first consulting a medical professional is incredibly dangerous and can lead to a variety of unpleasant side effects. 

You have an obligation to provide your doctor with complete and accurate information regarding your health history, particularly if you have ever been diagnosed with a liver ailment or any lung condition other than cancer, including any breathing problems, etc. Your doctor also needs to know if you are breastfeeding or if you are planning to breastfeed, as well as if you are pregnant or if you are trying to become pregnant.

If you are on this medicine, you are not allowed to breastfeed your child. It is also recommended that you discuss your diet and any supplements you use with your primary care physician. In addition, your doctor has to be aware of any other medications you are currently taking. 

Because of the potential for this medication to interact with other prescriptions, as well as the possibility that this medication could have the same effect on other medications, it is essential that you discuss all of your medications with your doctor.

How to take this medication?

  • You can take this drug once a day.

  • It comes in tablet form so you can have it orally.

  • Do not chew or suck the tablet, just gulp it down with the help of a glass of water. 

  • You can have it before or after your meals. 

  • It is recommended to have it on a fixed time every day for better results. 

  • The daily recommended dosage is 960 mg so you can have 8 tablets of 120 mg daily.

  • You must not stop taking the medicine until and unless your doctor prescribes you.

  • Discontinue the medication if you are unable to handle the dose of 240mg daily.

  • Do not do any dose reduction without consulting the doctor.

  • If you miss any dose or vomit after completing your dose by any chance, then do not take 2X dose next time. Just continue your regular medications.

Some of the common side effects of this medicine are: 

Like every other drug, this drug may also cause a few complications in the body. Some of the side effects of this drug are mentioned below.

  • Drug-induced liver injury

  • Hepatitis

  • Hepatotoxicity

  • Foetal pneumonitis/ Interstitial lung disease (ILD)  

  • Diarrhoea

  • Fatigue

  • Musculoskeletal pain

  • Cough

  • Rashes 

  • Arthralgia 

  • Constipation

Sotorasib comes in 120-mg tablets and is taken by mouth, once a day, and the recommended starting dose is 920 mg once a day( 8 tablets daily). Swallow the whole tablet always,do not crush or break it. Sotorasib can be taken with or without food, and needs to be taken around the same time each day.
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