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Lucicer is a second-generation selective inhibitor of anaplastic lymphoma kinase taken orally (ALK). By preventing ALK autophosphorylation, Lucicer disrupts downstream signaling cascades and slows the development of ALK-dependent cancer cells.
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Lucicer is a kinase inhibitor, which is a type of medication. It works by preventing cancer cells from developing by suppressing the action of an abnormal protein. Lucicer is a drug used to treat non-small cell lung cancer (NSCLC) caused by a mutation in the ALK gene (anaplastic lymphoma kinase). It's for people with advanced non-small-cell lung cancer (NSCLC) who have an FDA-approved test that shows their tumors are positive for anaplastic lymphoma kinase (ALK).