Capmatinib

Capmatinib is a drug used to treat individuals with metastatic non-small cell lung cancer (NSCLC) who have tumors that have an aberrant mesenchymal-epithelial transition (MET) gene. Capmatinib is utilized if your cancer has a specific genetic marker. This gene will be tested for by your doctor. Capmatinib belongs to the kinase inhibitor class of drugs. This slows or stops cancer cells from mutating.

Capmatinib is used to treat certain types of non-small cell lung cancer (NSCLC) that have spread to other parts of the body. Capmatinib belongs to a class of medications known as kinase inhibitors. A defective protein that signals cancer cells to multiply is blocked by this drug. It slows or stops the spread of cancer cells.

How to use Capmatinib 200 Mg Tablet

Capmatinib is available as an oral tablet. Most people take it twice daily, with or without food. Take CAPMATINIB every day at about the same time(s). Ask your doctor or pharmacist for clarification if you have any questions about the directions on your prescription label. Pay close attention to the CAPMATINIB directive. Do not take more often or in higher or lower amounts than recommended by your doctor.

•  Do not take another dose of CAPMATINIB if you vomit after taking it. Continue taking your medication as usual.
• Your treatment may need to be stopped temporarily or permanently by your doctor, or your dose of CAPMATINIB may need to be           reduced.
• The effectiveness of the medication and any negative side effects you encounter will determine this.
• Tell your doctor how you are feeling while being treated with CAPMATINIB.
• Ask your pharmacist or doctor for a copy of the manufacturer's information sheet for your patient.

Side Effects of Capmatinib

• Things to keep in mind regarding CAPMATINIB side effects:
• The majority of people won't experience all of the listed side effects.
• When it comes to the onset, duration, and severity of side effects, they are frequently predictable.
• Almost always, after treatment is over, side effects are curable and disappear.
• There are many ways to reduce or avoid side effects.

For patients taking CAPMATINIB, the following side effects are frequent (occurring in more than 30% of cases):

• Fatigue
• Hypoalbuminemia (low albumin)
• Increased blood amylase
• Increased liver enzymes (liver problem)
• Increased serum creatinine (kidney problem)
• Nausea and vomiting

For patients taking CAPMATINIB, these less frequent side effects (occurring in 10-29%) include:

• Back pain
• Chest pain (not related to the heart)
• Cough
• Decreased appetite
• Dyspnea (shortness of breath)
• Diarrhea or constipation
• Decreased appetite
• Fever
• Increased blood lipase
• Increased potassium (hyperkalemia)
• Reduced hemoglobin, leukocytes, and lymphocytes in low blood counts
• Low blood glucose (hypoglycemia)
• Low phosphorus (hypophosphatemia)
• Low sodium (hyponatremia)

These are uncommon but serious side effects that CAPMATINIB users may experience:

• Photosensitivity
• Pulmonary toxicity (damage to the lungs). A low-grade fever or dyspnea was common when this side effect occurred.

Not every adverse effect is mentioned above. The list does not include any side effects that are extremely rare, occurring in fewer than 10% of patients. However, you should always inform your doctor if you have any unusual symptoms.

What do you need to do when contacting your doctor?

Call your doctor right away if you notice any of the following signs, day or night

• A fever of 100.4oF (38oC) or higher, chills (signs of infection)
• having difficulty breathing, a cough, and/or a fever

The following symptoms require evaluation by a doctor but are not life-threatening. Within 24 hours of becoming aware of any of the following, get in touch with your healthcare provider:

nausea (which prevents one from eating and is not relieved by taking medicine as directed)

• uncommon bruising or bleeding
• the skin or eyes turning yellow
• stools with a light color or dark urine
• Stools that are dark or tarry, or that contain blood
• Urine with blood in it
• Urination may cause burning or pain.
• extreme tiredness (unable to carry on self-care activities)
• oral sores (painful redness, swelling, or ulcers)

Precautions that you should consider

• Before starting treatment with CAPMATINIB, talk to your doctor about all other medicines you are taking (including prescription and over-the-counter medicines, vitamins, herbal remedies, etc.). Unless your doctor expressly approves, avoid taking aspirin or aspirin-containing products.
• While taking CAPMATINIB, avoid getting any kind of vaccination or immunization without consulting your doctor first.
• Both men and women should: Use birth control and avoid becoming pregnant while taking CAPMATINIB. Condoms and other barrier methods of contraception are advised throughout treatment and for one week following the last dose of CAPMATINIB.
• Avoid breast-feeding while taking CAPMATINIB and for 1 week after your last dose.

Self-Care Tips

• Avoid crowds and sick people if you can, and notify your doctor right away if you experience fever or any other infection-related symptoms.
• Regularly wash your hands.
• To reduce bleeding, use a soft toothbrush and an electric razor.
• Take anti-nausea medications as directed by your doctor and consume small, frequent meals to lessen nausea.
• Observe the anti-diarrhea medication regimen that your doctor has advised.
• Consume foods that could prevent diarrhea (see managing side effects - diarrhea)
• Avoid being in the sun. Put on sunscreen with an SPF of 30 or higher and protective clothing.
• In general, it's best to limit or completely avoid drinking alcoholic beverages.
• Get lots of sleep.
• Maintain a healthy diet.
• As much as you are able, keep moving. Gentle exercise, such as daily walks, is encouraged.
• Be sure to discuss any symptoms or side effects you experience with your medical team. In addition to making other helpful suggestions, they can prescribe medications to treat such issues.

Frequently Asked Questions

Are there any other medicines available for this disease?

There might be additional medications to take into account for your condition. While some treatments are more successful than others, there is also a higher likelihood of adverse effects.

It's important to go over the benefits and drawbacks of each medication option with your doctor. There may be many different drug prices, so you should find out if there are any less expensive alternatives.

What is the best way to take the medicine and for how long should I take it?

There are a few medications for this condition that come in tablet, pill, powder, and liquid form. Others are taken multiple times throughout the day, while some are taken only once a day or once a week. Regardless of the medication, it is crucial to discuss how and when to take it with your doctor. Additionally, you have the option of consulting the CMI or a pharmacist.

When and how will I know if the medication is effective?

While some medications begin to show results almost immediately, others, like some, may take weeks. Before you begin taking a medication, ask your doctor or pharmacist how long it will take for it to start working and how you will know if it is.

Should I be aware of any potential side effects?

Side effects are the unfavorable effects of medication. Most medications have the potential to cause side effects, but not everyone will have them. It's essential to be aware of medication side effects so you can react appropriately if you do.

Always ask your doctor for advice and information about:

Common side effects are typically less severe but more frequent than serious side effects. —These are extremely uncommon side effects, but they may have more severe consequences.

What are the possible advantages of using this medication?

There are numerous ways that medications work. Few medications can treat all or even some of a disease's symptoms, but others can prevent illness or its negative effects. Ask your doctor to explain the benefits of the medication, and then think about what those benefits mean to you. For any medication, you take, follow your doctor's advice!

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